Poseida Therapeutics, Inc. (Nasdaq: PSTX), a clinical-stage allogeneic cell therapy and genetic medicines company advancing differentiated non-viral treatments for patients with cancer, autoimmune and rare diseases, announced new preclinical data on allogeneic CAR+TCR-T cells rich in stem cell memory T cells (T_SCM), along with platform enhancements aimed at enhancing potency and improving targeting of solid tumors, will be presented at the Society for Immunotherapy of Cancer (SITC) 39^th Annual Meeting in Houston, November 6-10.

Additionally, the Company announced presentations at the 66^th American Society of Hematology (ASH) Annual Meeting & Exposition, which will be held December 7-10 in San Diego. To further characterize compelling emerging P-BCMA-ALLO1 clinical data, additional profiling of patient responses from the optimized lymphodepletion arm (Arm C) of the P-BCMA-ALLO1 Phase 1 study, along with data first presented at the 21st International Myeloma Society (IMS) Annual Meeting will be highlighted as a poster presentation. In addition, preclinical data from the ongoing Phase 1 trial of P-CD19CD20-ALLO1 in patients with B-cell malignancies will be delivered as a poster presentation.

P-BCMA-ALLO1 is an investigational non-viral T_SCM-rich allogeneic CAR-T therapy in Phase 1/1b clinical development. This investigational off-the-shelf allogeneic CAR-T cell therapy targeting BCMA has received Regenerative Medicine Advanced Therapy (RMAT) designation for adult patients with relapsed/refractory multiple myeloma after three or more prior lines of therapies. P-CD19CD20-ALLO1, the Company's first allogeneic dual CAR-T cell product candidate, targets both CD19 and CD20 antigens for the treatment of relapsed or refractory B-cell malignancies. The Company is developing P-BCMA-ALLO1 and P-CD19CD20-ALLO1 as part of a broader collaboration with Roche focused on addressing hematologic malignancies with Poseida's T_SCM-rich CAR-T platform.