MEDiC Life Sciences Announces Collaboration with Bristol Myers Squibb on Tumor Target Discovery

06 June 2023 | Tuesday | News

MEDiC Life Sciences (“MEDiC”), a Silicon Valley biotech startup, today announced that it entered into a research collaboration with Bristol Myers Squibb (NYSE:BMY). In the collaboration, MEDiC is using its scalable 3-dimensional tumor models to perform CRISPR functional genomics screens in solid tumor indications of interest to Bristol Myers Squibb. MEDiC is also using its immune cell and tumor cell co-culture platform to identify novel genes relevant to immune cell killing of cancer cells.
Image Source | Public Domain

Image Source | Public Domain

“We are very excited that Bristol Myers Squibb selected MEDiC as a collaborator to advance its oncology discovery programs,” said Kyuho Han, Ph.D., co-founder and chief executive officer of MEDiC. “We look forward to working with Bristol Myers Squibb to identify novel oncology targets to advance potentially effective new medicines for cancer patients.”

Under the terms of the agreement, MEDiC will receive upfront payments for the research collaboration and will be eligible for additional option payments on a target-by-target basis. MEDiC is also eligible for future development and regulatory milestone payments.

MEDiC has developed a proprietary CRISPR functional genomics platform that employs patient-tumor-like cancer models to identify optimal gene targets and biomarkers for cancer. While functional genomics approaches have been widely used to screen whole genomes for gene functions in cancer, MEDiC has demonstrated for the first time that using 3-dimensional tumor models, rather than traditional 2-dimensional cultures, may vastly improve the accuracy and translatability of CRISPR functional genomics. With this technology, MEDiC may identify novel cancer targets and biomarkers to develop drugs for solid tumor indications. MEDiC’s unique approach has already attracted partners seeking novel targets for drug development.

 

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