This collaboration occurs in the wake of recent advancements from GERO, which sparked vigorous discussion among longevity experts in the scientific community when a story was published in Popular Mechanics that asserted Humans Can Stop—But Not Fully Reverse—Aging. GERO’s machine-learning technology platform is being applied to discover potential therapeutic targets for fibrotic diseases using large-scale human data in collaboration with a large biopharma.

What this means for wellness and longevity

FOXO Technology’s unique datasets are a missing link in understanding the utility, reliability, and reversibility of epigenetic signatures of health and longevity. Augmented by GERO´s AI-driven understanding of human aging, this collaboration promises to enhance risk segmentation of individuals based on longitudinal changes in their epigenetic patterns. The overarching goal of this joint effort is to uncover new ways to personalize lifestyle-based interventions to delay the onset of chronic diseases and, ultimately, mortality.

What this means for longevity biotechnology

GERO and FOXO share the goal of helping people live healthier for longer, whether through the development of new diagnostics and therapeutics, or by lifestyle modifications. FOXO’s founding was based, in part, on the discovery of “epigenetic clocks” — a benchmark measure of biological aging, in which FOXO’s Chief Science Officer Dr. Brian Chen played a key role in demonstrating its utility. Since its founding, FOXO has generated data and partnerships to accelerate the development and commercialization of epigenetic signatures with the goal of gaining unique insights to one’s health and longevity.

Dr. Peter Fedichev [CEO and co-founder of GERO], sees enormous promise for the insights derived from longitudinal epigenetic data to address life and health span.

“Our goal is to slow down or even stop human aging. Epigenetics has revolutionized the way in which the field has thought about biological aging, but we have only scratched the surface. With FOXO’s unique expertise and resources, we hope to unlock more nuanced relationships between epigenetics and aging that haven’t been previously understood,” commented Fedichev.

GERO invites partnerships for novel target identification and comprehensive drug discovery collaborations, as exemplified by its recent work with a biopharma leader. GERO’s scientific excellence and outstanding drug-discovery capabilities are the basis for the range of landmark papers in aging and drug discovery fields that shape the future of the industry, published in numerous magazines, including Nature Communications (1, 2, 3), and Science journals and are covered by Scientific American, Popular Mechanics (5, 6), and other media outlets.