Parse Biosciences, a pioneering provider of accessible and scalable single cell sequencing solutions, has announced a significant update to its flagship Evercode™ Whole Transcriptome products. Set to be available for shipment in mid-March, Evercode Whole Transcriptome version 3 kits present researchers with a more refined workflow, enhanced flexibility, and increased throughput fixation capabilities, along with optimized reagents for heightened sensitivity in gene detection.

"With this new version, we're delivering tools that excel in sensitivity, scalability, and flexibility, addressing the evolving needs of researchers," commented Parse Biosciences co-founder and CTO, Charlie Roco. "Our mission has always been to democratize single cell research, and the enthusiastic response from the scientific community to Evercode reflects its impact and value."

The latest version promises customers a streamlined and adaptable workflow, facilitating faster transitions from samples to results. Notably, these improvements come alongside substantial enhancements in sensitivity and library complexity, empowering researchers with greater biological resolution and deeper insights into their samples.

Parse customers have long relied on the utility of Evercode fixation, enabling them to fix cells or nuclei when available, store them for up to six months, and subsequently sequence them as needed. Version 3 introduces the ability to fix up to 96 samples simultaneously in plate format, an invaluable enhancement for high-throughput drug screening and large cohort patient sample profiling.

Evercode Whole Transcriptome version 3 chemistry is compatible across the entire product line, including WT Mini for experiments up to 10,000 cells or nuclei, WT for experiments up to 100,000 cells or nuclei, WT Mega for experiments up to 1,000,000 cells or nuclei, and Fixation for cells or nuclei.

Launched in 2021, Evercode split-pool combinatorial barcoding offers a straightforward, instrument-free solution to single cell RNA sequencing, attracting over 1,500 labs worldwide for its scalability, adaptability, and quality assurance.