Both presentations are from the company’s CORAL program, which is evaluating various self-amplifying mRNA (samRNA) vaccine candidates targeting Spike in addition to other viral genes of SARS-CoV-2. The program aims to serve as proof-of-concept for Gritstone’s infectious disease vaccine approach and the potential application of samRNA against infectious diseases.

Abstract details associated with these presentations are available on the conference website.

Presentation details:

• Abstract 03190 (Poster Presentation): Study of Self-amplifying mRNA (samRNA) Vaccine Candidates Against COVID-19 in Healthy Adults and People Living with Human Immunodeficiency Virus (HIV) in South Africa
  Date/Time: Monday Apr 17, 2023, 12:00 PM GMT+1
  Session: 12g. Vaccine development, trials, efficacy, policy
  Presenter: Atul Nagare, MD
  Location: Poster P2715, Poster Arena, Bella Center Copenhagen

• Abstract 03157 (ePoster Flash Session): First Study of a Self-amplifying mRNA (samRNA) Vaccine, GRT-R910, as a COVID-19 Boost in Healthy Volunteers ≥60 Years of Age: Preliminary Evidence of Sustained Immunogenicity
  Date/Time: Monday Apr 17, 2023, 8:30 AM GMT+1
  Session: Age-related susceptibility to COVID and risks in long-term facilities
  Presenter: Pedro Garbes, MD, MSc.
  Location: Arena 1, Bella Center Copenhagen