Harbour BioMed Initiates Phase I Study of First-in-Class Antibody HBM1020

05 June 2023 | Monday | News

Harbour BioMed (HKEX: 02142) announced that the first patient has been dosed in its ongoing phase I trial of the first-in-class anti-B7H7 (HHLA2) antibody HBM1020 (NCT05824663/Study 1020.1) in the United States. This study is evaluating the safety, tolerability, pharmacokinetics, and anti-tumor activity of HBM1020 in patients with advanced solid tumors.
Image Source | Public Domain

Image Source | Public Domain

 

  • HBM1020 is a first-in-class therapeutic monoclonal antibody against B7H7/HHLA2 entering clinical development globally.
  • HBM1020 was generated from Harbour Mice® H2L2 transgenic mice platform.
  • HBM1020 has great potential to address huge unmet medical needs in patients with advanced malignancies.

HBM1020, generated from Harbour Mice® H2L2 transgenic mice platform, is the first therapeutic monoclonal antibody against B7H7/HHLA2 entering clinical development globally.

"We are delighted to announce the dosing of the first patient with our first-in-class B7H7/HHLA2 antibody HBM1020," said Dr. Jingsong Wang, Founder, Chairman and Chief Executive Officer of Harbour BioMed. "This milestone is a significant accomplishment for our team and represents a major step forward in our mission to transform patient care. We are excited about the potential of the B7H7/HHLA2 antibody to make a meaningful difference in the lives of patients suffering from advanced malignancies and we remain dedicated to advancing its clinical development globally."

 

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