Amarna Therapeutics, (“Amarna” or “the Company”), a privately held biotechnology company specializing in transformative gene therapies, is pleased to announce its strategic collaboration with NorthX Biologics, a leading biologics manufacturing partner. This partnership represents a major step in advancing the clinical trial manufacturing of Nimvec™ AM510, Amarna’s groundbreaking gene therapy platform designed to transform the treatment of immune-mediated diseases. The collaboration will begin with the transfer of Amarna’s research-scale production process for Nimvec™ AM510 to NorthX Biologics. This critical step initiates the Chemistry, Manufacturing, and Controls (CMC) development process at NorthX, laying the groundwork for cGMP-compliant manufacturing to support First-in-Human (FiH) clinical trials. Together, the companies will focus on optimizing and scaling production processes to ensure high-quality, safe, and effective therapies for future clinical applications.

A Shared Vision for Transformative Gene Therapy
This partnership highlights the shared commitment of Amarna Therapeutics and NorthX Biologics to advance innovative solutions in gene therapy. By combining Amarna’s cutting-edge Nimvec™ platform with NorthX’s world-class expertise in biologics manufacturing, the collaboration aims to address unmet medical needs and set new standards for therapeutic development. “We are delighted to partner with NorthX Biologics, whose proven expertise in biologics manufacturing perfectly complements our vision of delivering transformative gene therapies,” said Henk Streefkerk, CEO of Amarna Therapeutics. “This collaboration is a pivotal milestone in bringing Nimvec™ AM510 closer to clinical application.

”We are excited to collaborate with the Amarna team, allowing us to leverage NorthX Biologics’ expertise in viral vector manufacturing, to support the development of this pioneering gene therapy platform. Together, we aim to accelerate the journey of Nimvec™ AM510 toward providing life-changing treatments for patients in need," said Janet Hoogstraate, CEO of NorthX Biologics.

Looking Ahead
This partnership embodies a shared vision to revolutionize gene therapy through scalable innovation. By uniting their expertise, Amarna Therapeutics and NorthX Biologics are set to advance transformative therapies that enhance patient outcomes while establishing new standards in therapeutic development and manufacturing excellence. Additionally, this collaboration enables the production of batches for future products, supporting the development of groundbreaking treatments yet to come.