BriaCell Partners with Memorial Sloan Kettering to Accelerate Development of Next-Generation Personalized Immunotherapy

22 October 2025 | Wednesday | News

Through MSK’s Therapeutics Accelerator Program, BriaCell will advance manufacturing, IND preparation, and Phase 1 clinical development of its Bria-OTS+™ platform, including Bria-BRES+™ for metastatic breast cancer.

  • Collaboration with MSK’s Therapeutics Accelerator Program includes manufacturing, IND and clinical development support of the Bria-OTS+™ platform, which includes Bria-BRES+™ for breast cancer

 BriaCell Therapeutics Corp. (Nasdaq: BCTX, BCTXW, BCTXZ), (TSX: BCT) (“BriaCell” or the “Company”), a clinical-stage biotechnology company that develops novel immunotherapies to transform cancer care, is pleased to announce a collaboration with Memorial Sloan Kettering Cancer Center’s (MSK’s) Therapeutics Accelerator Cohort program to accelerate the clinical development of Bria-OTS+, BriaCell’s next generation personalized off-the-shelf immunotherapy, for multiple cancer indications including metastatic breast cancer, prostate cancer, and other cancers.

The collaboration starts with manufacturing, IND development and clinical protocol support for a Phase 1 clinical trial with Bria-BRES+, BriaCell’s next generation personalized immunotherapy for patients with breast cancer under the Bria-OTS+ platform.   The partnership expands on BriaCell’s previously-announced selection into MSK’s accelerator program.

As one of the world’s foremost cancer research and treatment institutions, MSK has more than 135 years of leadership in patient care, education and discovery. Through the MSK Therapeutics Accelerator, MSK’s therapeutic-based strategic collaboration program, BriaCell will obtain access to MSK’s clinical and institutional expertise, including cell therapy manufacturing, Investigational New Drug (IND) preparation and submission and clinical development to expedite development of the Bria-OTS+ platform.

“We are thrilled to collaborate with MSK’s scientific and clinical experts to address the urgent unmet medical need of many thousands of metastatic breast cancer patients,” stated Dr. William V. Williams, BriaCell’s President and CEO.

“We are honored to be working with the team of cancer specialists at MSK,” noted Miguel Lopez-Lago, PhD, BriaCell’s Chief Scientific Officer. “This collaboration with MSK will accelerate the development of our advanced personalized off-the-shelf immunotherapy platform, Bria-OTS+, which we believe has the potential to transform cancer care and significantly improve patients’ lives through its unique mechanism of action.”

“We look forward to working with BriaCell through MSK’s Therapeutics Accelerator to help advance this next-generation personalized immunotherapy into the clinic.  Collaborations like this are essential to translating promising scientific innovations into potential new treatment options for patients,” commented Shanu Modi, MD, Breast Medical Oncologist and Attending Physician at MSK.

 

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