Proton Intelligence Secures $6.95M Seed Funding to Advance Continuous Potassium Monitoring for Cardio-Kidney-Metabolic Care

26 December 2024 | Thursday | News

With backing from leading investors, the CKM™ platform aims to transform patient outcomes by providing real-time potassium monitoring to address critical gaps in managing chronic kidney and heart diseases.
Picture Courtesy | Public Domain

Picture Courtesy | Public Domain

Proton Intelligence Inc., developing the first-ever Continuous Potassium Monitoring (CKM™) platform,  announced the closing of its $6.95 million USD Seed Financing round joined by SOSV, We Venture Capital, Tenmile, LongeVC, 15th Rock, Exor, and Trampoline Venture Partners.

The CKM™ platform is designed to transform the management of cardio-kidney-metabolic diseases by providing clinicians and patients crucial data about potassium levels on-demand. Potassium is both the most important biomarker in cardiac-kidney-metabolic diseases and the hardest to measure. Dangerous fluctuations in potassium levels—whether too high or too low—lead to cardiac arrhythmias and sudden cardiac death. The inability to provide timely potassium levels to patients and providers is a major barrier to getting patients on the correct life-saving therapies. About 33% of people with chronic kidney disease (CKD) or heart failure (HF) unnecessarily stop life-saving therapy after a high potassium event, which ultimately results in a nearly 40% increase in 6-month mortality [1]. Proton’s CKM™ technology aims to provide providers and patients accurate, remote, continuous potassium levels allowing precise treatment of patients suffering from kidney disease or heart failure.

"We are proud to be the first institutional investor in Proton Intelligence," said Mohan S. Iyer, General Partner at SOSV. "The team's exceptional focus and relentless execution inspire confidence, and we are excited to continue to support them as they move into clinical validation.”

“We Venture Capital have been impressed by this true breakthrough in electrolyte sensing capability, which will fulfil a critical gap in the current care continuum for many patients at risk from dyskalemia. We look forward to working with the Proton Intelligence team on the next phase of their journey,” said Dr. Louise Warme, Head of We Venture Capital.

The company has initiated clinical studies assessing the performance of CKM™ in people living with severely impaired kidney function such as the underserved population living with end-stage renal disease (ESRD) or chronic kidney disease (CKD). According to the United States Renal Data System (USRDS), 14% of US adults have CKD and account >25% of Medicare spend. Patients with ESRD account for 7% of US Medicare expenditure annually [2].

“The ability to continuously monitor potassium will enable better data driven decision making for patients with late-stage chronic kidney disease or on dialysis, not only improving outcomes for these patients but saving health systems considerable costs,” said Dr. Steve Burnell, Managing Director at Tenmile.

“This fundraising milestone represents a major leap forward for us,” said Dr. Sahan Ranamukhaarachchi, Founder and CEO of Proton Intelligence Inc. “We are immensely grateful for the trust and support of our investors, who share our vision of revolutionizing cardio-kidney-metabolic care. Their belief in our mission sees us funded through a number of clinical feasibility trials ahead of a pivotal study planned for 2026 and get closer to making CKM™ a reality for millions of patients.”

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