New Study Highlights the Complexity of Using Antiviral Drug Combinations for HIV Prevention

06 April 2023 | Thursday | News

Researchers at the Oak Crest Institute of Science have been exploring new ways to prevent the spread of HIV-1 among adolescent girls and young women in low and middle income countries, who are disproportionately affected by HIV-1.
Experimental design of BLT hu-mouse vaginal HIV-1 prevention studies

Experimental design of BLT hu-mouse vaginal HIV-1 prevention studies

One promising approach involves delivering antiviral compounds vaginally, using inserts, gels, films, or intravaginal rings. This method is appealing because it is women-controlled and topical, potentially reducing systemic exposure to the agents. However, a fundamental question remains: how many drugs are needed for an effective product, and are three drugs better than two? Some of these questions have been answered in a new study, and the answers may be surprising.

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