• A type of artificial intelligence (AI), Deep Learning (DL) technology can advance medical imaging capabilities by providing more robust, accurate, and data-driven information as well as support more efficient workflows and exams
• Precision DL for PET/CT is the latest addition to GE HealthCare’s Effortless Recon DL portfolio of deep learning-based solutions – which also includes AIR Recon DL for MRI, TrueFidelity for CT, and Helix DL for X-ray – to significantly improve image quality and help better inform clinical decision-making for improved patient outcomes

Together, the availability of Precision DL with Omni Legend’s ultra-high sensitivity, third generation digital detector technology marks a new era for PET/CT performance and outcomes, transitioning from ToF technology to the next generation of PET/CT performance and enabling clinicians to decode coincidence events at exceptionally fine resolutions for informed diagnoses and treatment planning.

“We can’t treat what we don’t see, which is why we require precise image quality to help diagnose, plan treatment for, and monitor disease,” explains Prof. Flavio Forrer, MD, PhD, Chairman of Nuclear Medicine in the Division of Radiology and Nuclear Medicine at Kantonsspital St. Gallen in Switzerland^vii. “Precision DL enhances image quality – enabling us to spot small lesions, including on images obtained with very low dose injections and short bedtimes, to potentially start treatment and monitoring early, which might result in improved patient outcomes. Additionally, Omni Legend offers a streamlined, simple solution that helps enable technologists to increase efficiency, enhance patient care, and reduce potential radiation exposure to medical staff ^vii.”

Medical imaging is a crucial tool for diagnosing disease, identifying a course of treatment, and determining whether therapy is successful for millions of patients around the world. Image quality matters – to the clinician and the patient – making the difference between finding a small lesion early or in its later stages, potentially affecting patient outcomes and disease management. For this reason, clinicians are increasingly adopting AI-based solutions for enhanced image quality compared to that of standard care.

A subset of AI and machine learning, deep learning utilizes deep neural networks, which consist of layers of mathematical equations and millions of connections and parameters that are trained and strengthened based on the desired output. In doing so, deep learning is a significant leap forward in efficacy compared to previous processes that require more human intervention, handling complex models and vast numbers of parameters with ease to help provide clinicians the time and insights they need to more confidently diagnose and care for patients.

“One of the main advantages of moving fully into the future of AI and deep learning is making state-of-the-art imaging accessible to more practices, across more care areas than ever before,” shares Jan Makela, President & CEO, Imaging, GE HealthCare. “Clinicians are seeing the value of applying deep learning technology to enhance image quality with our multi-modality family of Effortless Recon DL applications, which already includes AIR Recon DL for MR, TrueFidelity for CT, and Helix DL for X-ray. Now we are proud to add Precision DL for PET/CT, enabling more precise and personalized care across healthcare systems’ imaging departments.”

More than a new imaging processing technique, Precision DL was engineered with a sophisticated deep neural network trained on thousands of images created with multiple reconstruction methods, including ToF reconstruction, to provide the image quality performance benefits typically associated with hardware-based ToF reconstruction, such as improved contrast-to-noise ratio and contrast recoveryⁱ.

Precision DL processes patient images for enhanced image quality, including:

• 11% improvement on average in contrast recoveryⁱ,
• 23% improvement on average in contrast-to-noise ratioⁱ,
• 42% increase on average in small, low contrast lesion detectability^viii, and
• 14% improvement feature quantification accuracyⁱⁱ.

Altogether, a study published in the European Journal of Nuclear Medicine and Molecular Imaging, demonstrated improvement in feature quantitation, overall image sharpness, and overall diagnostic value, particularly in terms of lesion detectability and diagnostic confidence of PET/CT images reconstructed without ToF using deep learning models trained for ToF image enhancement^ix.

GE HealthCare’s deep-learning-enabled software is revolutionizing image acquisition and reconstruction in MR, CT, X-ray and now PET/CT, empowering clinicians and helping improve patient outcomes.