Senti Bio Receives FDA Clearance for SENTI-202 in Hematologic Malignancies

Initial clinical efficacy data expected by year-end 2024 and durability data expected in 2025 – – SENTI-202 is a potential first-in-class of...

December 26, 2023 | Tuesday | News
AlloVir Updates Phase 3 Program for Posoleucel T Cell Therapy

Company to discontinue its three Phase 3 posoleucel studies following separate, pre-planned DSMB futility analyses concluding the studies were unlikely to ...

December 26, 2023 | Tuesday | News
Thermo Fisher's PPD to Aid BARDA in Phase II ARDS Clinical Trial

ARDS is a life-threatening lung condition with multiple causes, including severe pneumonia and sepsis due to bacterial and viral infections such as influen...

December 22, 2023 | Friday | News
Inventiva Enrolls First Patient in China for NATiV3 Trial and Updates Clinical Development Program

The first patient was randomized in China in the NATiV3 Phase III clinical trial, triggering a milestone payment of $3 million from CTTQ to Inventiva.&nb...

December 21, 2023 | Thursday | News
Sanofi Ends Tusamitamab Ravtansine Program Due to Phase 3 Trial Setback in 2L NSCLC

CARMEN-LC03 trial did not meet dual primary endpoint of improving progression-free survival; tusamitamab ravtansine clinical development program will be ...

December 21, 2023 | Thursday | News
Compass Pathways reports positive tolerability results for investigational COMP360 psilocybin treatment in Phase 2 study for post-traumatic stress disorder

Compass Pathways plc (Nasdaq: CMPS) (“Compass”), a biotechnology company dedicated to accelerating patient access to evidence-based innovation ...

December 20, 2023 | Wednesday | News
Carina Biotech Doses First Australian Patient in LGR5 CAR-T Trial

First patient dosed in Australia where 3 clinical trial sites have been activated. The trial will enrol advanced colorectal cancer patients whose cancer...

December 19, 2023 | Tuesday | News
First patient in China has been dosed in the YOLT-201 clinical trial for the treatment of Hereditary ATTR-CM

The study by YolTech is a single-arm, open-label, dose-escalation clinical trial (Clinicaltrials.gov: NCT06082050). This trial's primary objectives are to ...

December 18, 2023 | Monday | News
AstraZeneca to Acquire Icosavax, Including Promising Phase II RSV and hMPV Combination Vaccine

AstraZeneca has entered into a definitive agreement to acquire Icosavax, Inc. (NASDAQ: ICVX), a US-based clinical-stage biopharmaceutical company focused o...

December 12, 2023 | Tuesday | News
Mabwell's Novel Nectin-4 ADC Granted CDE Approval for Phase III Trial

9MW2821 is a novel Nectin-4 targeting ADC developed independently by Mabwell, marking the first of its kind among the products developed in China with the ...

December 11, 2023 | Monday | News
Bristol Myers Squibb's Opdivo and Yervoy Combo Shows Positive Results in Phase 3 Trial for Metastatic Colorectal Cancer

Opdivo (nivolumab) plus Yervoy (ipilimumab) demonstrates statistically significant and clinically meaningful improvement in progression-free survival compa...

December 08, 2023 | Friday | News
Cyprium Transfers CUTX-101 for Menkes Disease to Sentynl, a Zydus Lifesciences Subsidiary

Cyprium received $4.5 million payment upon closing and remains eligible to receive royalties and up to $129 million in aggregate development and sales mile...

December 07, 2023 | Thursday | News
ObvioHealth Launches Unique eCOA Solution for Improved Clinical Trial Measurement.

 ObvioHealth, a global digital clinical trials company delivering stronger clinical evidence through tech-enabled trials, has launched an innovative e...

December 06, 2023 | Wednesday | News
Merck Updates on Phase III Evobrutinib Results in Relapsing MS

Results from the EVOLUTION clinical trials showed evobrutinib did not meet its primary endpoint of annualized relapse rate for up to 156 weeks compared to ...

December 06, 2023 | Wednesday | News

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