OmniScience and INmune Bio announced a pioneering partnership to revolutionize operations for INmune Bio’s global Phase 2 Alzheimer’s disease (AD) clinical trial (the “AD02 trial”) using OmniScience’s flagship product, Vivo, an industry-first, genAI-powered control tower designed specifically for centralizing and analyzing vast clinical data in real time. This solution represents a innovative approach to clinical research, delivering immediate insights that enhance decision-making and transform traditional, time-consuming trial management.

Vivo securely unifies data across sources including electronic data capture (EDC), clinical trial management systems (CTMS), patient-reported outcomes (PROs)/clinical outcome assessments (COAs), labs, sensors/wearables, safety databases, and more. With fully integrated data, Vivo goes beyond dashboard visualizations to enable clinical trial teams to improve their decision-making, accelerate timelines, enhance patient safety, and ultimately improve health outcomes. Designed with explainability and interpretability at its core, Vivo ensures that every generated insight is supported by clear, traceable rationale grounded in data and clinical context. Its advanced cognitive architecture combines ontological knowledge of trial protocols with domain-specific clinical expertise, enabling qualitative and quantitative reasoning at scale.

INmune Bio recently announced it completed randomization of patients for its blinded AD02 trial for patients with early AD and biomarkers of elevated neuroinflammation. The trial overenrolled with a total of 208 patients, 56% of whom were categorized as mild AD and 44% as mild cognitive impairment. INmune Bio plans to release top-line cognitive results in the second quarter of 2025.

“A global trial of this size is vast, and Vivo will be critical in our ability to analyze cognitive results,” stated Tara Lehner, INmune Bio’s VP of Clinical Operations. “With genAI provided by Vivo, we can amplify our clinical teams’ capabilities, turning complex data into actionable insights at unprecedented speed, which means we can get answers—and treatments—to patients faster.”

INmune and OmniScience partnered throughout Vivo’s product development and have completed the first phase of Vivo’s roll-out to INmune’s clinical development team. Throughout the initial rollout, significant beneficial findings include:

• Improved data quality through Vivo’s automatic identification of data discrepancies
• Enhanced visualization of COAs, supporting identification of outliers and better understanding of population distributions
• Real-time answers, supporting decisions on patient enrollment criteria, even while the patient is in the clinic
• Reduced reliance on time-consuming spreadsheet-based data analysis, improving collaboration between clinical and executive teams

“OmniScience and INmune Bio share a vision to transform how clinical trial teams engage with data – transforming data into knowledge in real time and informing decisions that increase the probability of success,” shared Angela Holmes, CEO of OmniScience. “As our partnership moves forward, we’re gaining further insights from the INmune team that we can integrate into Vivo’s roadmap. We look forward to our continued mutual success.”

“The future of clinical trials demands smarter solutions, and Vivo embodies this shift,” explained Michael Bell, VP of Product, OmniScience. “Through this collaboration, INmune Bio provides continuous feedback that enables OmniScience’s development team to evolve Vivo. This hands-on approach builds confidence among users, who see firsthand how genAI can rapidly turn data into answers and transform their day-to-day workflows.”